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Pyrazole, 3-amino-4-cyano-5-ethyl- → 2-Ethyl-7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Pyrazole, 3-amino-4-cyano-5-ethyl- | HCID 114021 | — |
| 反応物 | 3-(Dimethylamino)-1-phenyl-2-propen-1-one | HCID 353460 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2-Ethyl-7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonitrile | HCID 23329865 | — |
反応手順
A mixture of 0.71 g. of 3-dimethylaminoacrylophenone, 15 ml. of glacial acetic acid and 0.55 g. of 3-amino-5-ethylpyrazole-4-carbonitrile is refluxed for 16 hours and then evaporated. The residue is treated as described in Example 1, giving the desired product, m.p. 132°-134° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04236005 |
| 出典データセット | uspto-grants-1980_11 |
| ORD ID | ord-c03202d10e164bc3992b5fcb05806c0a |
| 出典メモ | uspto-grants-1980_11 |