反応式
Cl.[NH2:2][C:3]1[N:4]=[CH:5][NH:6][C:7]=1[C:8]([NH2:10])=[O:9].CN(C)[CH:13]=[CH:14][C:15]([C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([C:23]([F:26])([F:25])[F:24])[CH:18]=1)=O.C([O-])(=O)C.[Na+]>C(O)(=O)C>[F:24][C:23]([F:25])([F:26])[C:19]1[CH:20]=[CH:21][CH:22]=[C:17]([C:15]2[N:4]3[CH:5]=[N:6][C:7]([C:8]([NH2:10])=[O:9])=[C:3]3[N:2]=[CH:13][CH:14]=2)[CH:18]=1参加物
5
実験手順
A mixture of 1.62 g. of 4-amino-5-imidazolecarboxamide hydrochloride, 2.43 g. of 3-dimethylamino-3'-trifluoromethylacrylophenone and 0.82 g. of sodium acetate in 25 ml. of glacial acetic acid is refluxed for 15 hours and then evaporated to dryness. The residue is treated as described in Example 1, giving the desired product, m.p. 239°-240° C.
後処理
- additionA mixture of 1.62 g
- customevaporated to dryness
- additionThe residue is treated
出典と根拠
- ORDレコード
- ord-c4aca6425bf1473183d71155aea10868
- 出典データセット
- uspto-grants-1980_11
- 特許番号
- US04236005
関連ノート
読み込み中…