3,4-Dimethoxyphenyl methyl ketone → (E)-1-(3,4-dimethoxyphenyl)-3-(dimethylamino)-2-propen-1-one

HRID 225279

反応式

HRID 225279 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11](=[O:13])[CH3:12])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].CO[CH:16](OC)[N:17]([CH3:19])[CH3:18]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11](=[O:13])[CH:12]=[CH:16][N:17]([CH3:19])[CH3:18])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

参加物

3

反応物 2

HCID 143283,4-Dimethoxyphenyl methyl ketoneHCID 78373Dimethylformamide dimethyl acetal

生成物 1

HCID 1481361(E)-1-(3,4-dimethoxyphenyl)-3-(dimethylamino)-2-propen-1-one

実験手順

A mixture of 50.0 g. of 3',4'-dimethoxyacetophenone and 50 ml. of dimethylformamide dimethylacetal is refluxed for 16 hours. On cooling the desired compound crystallizes from solution. Hexane is added and the material is recovered by filtration, m.p. 124°-125° C.

後処理

  1. additionA mixture of 50.0 g

出典と根拠

ORDレコード
ord-54c4480f822a4aa3a9d351bb9039ec04
出典データセット
uspto-grants-1980_11
特許番号
US04236005

関連ノート

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