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3',4'-Dimethyl-3-dimethylaminoacrylophenone → Ethyl 7-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3',4'-Dimethyl-3-dimethylaminoacrylophenone | HCID 54311844 | — |
| 反応物 | HCID 178469928 | HCID 178469928 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | Ethyl 7-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate | HCID 11346960 | — |
反応手順
A mixture of 4.06 g. of 3',4'-dimethyl-3-dimethylaminoacrylophenone and 3.10 g. of ethyl 3-aminopyrazole-4-carboxylate in 25 ml. of glacial acetic acid is refluxed for 6 hours. The desired compound is recovered as in previous examples except that the compound as first observed is amorphous and then crystallizes on standing in the crystallization solvent, m.p. 187°-188° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04236005 |
| 出典データセット | uspto-grants-1980_11 |
| ORD ID | ord-62e38a1efe7b44b5b4f7de60b49e8639 |
| 出典メモ | uspto-grants-1980_11 |