化工社化工社 化学情報印刷レポート · 研究参考用
Hydrogen Bromide → (-)-alpha-Amino-3-(bromomethyl)-4-hydroxybenzeneacetic acid hydrobromide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrogen Bromide | HCID 260 | — |
| 反応物 | Formaldehyde | HCID 712 | — |
| 反応物 | 4-Hydroxyphenylglycine | HCID 92143 | — |
| 生成物 | (-)-alpha-Amino-3-(bromomethyl)-4-hydroxybenzeneacetic acid hydrobromide | HCID 70576814 | — |
反応手順
To a solution of (-)-α-amino-4-hydroxybenzeneacetic acid (0.6 mole) in a minimum amount of concentrated hydrobromic acid at 35°-40° C. is added 50 ml of aqueous formaldehyde (35-37%) (0.6 mole). The addition of hydrogen bromide gas is begun. After 5-10 minutes, a solid begins to precipitate. Stirring is continued for 30 minutes. The title compound is collected and washed with ether and acetone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04236002 |
| 出典データセット | uspto-grants-1980_11 |
| ORD ID | ord-bfac019684294d10844af47e66f9c982 |
| 出典メモ | uspto-grants-1980_11 |