Phenolphthalein → (-)-alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester
反応式
Cl.[CH3:2][O:3][C:4](=[O:17])[CH:5]([NH2:16])[C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[C:8]([CH2:13][O:14][CH3:15])[CH:7]=1.[OH-].[K+].C1C=CC2C(C3C=CC(O)=CC=3)(C3C=CC(O)=CC=3)OC(=O)C=2C=1>CO>[CH3:2][O:3][C:4](=[O:17])[CH:5]([NH2:16])[C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[C:8]([CH2:13][O:14][CH3:15])[CH:7]=1参加物
5
実験手順
(-)-α-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester hydrochloride is dissolved in a minimum amount of methanol. To this solution is added methanolic potassium hydroxide until a basic reaction to phenolphthalein is observed. The potassium chloride which precipitates is removed and the solvent is removed under vacuum to give a quantitative yield of the title compound.