化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | (-)-alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester | HCID 53644499 | — |
| 溶媒 | Sodium Hydroxide | HCID 14798 | — |
| 生成物 | alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid | HCID 23329768 | — |
反応手順
(-)-α-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester is dissolved in aqueous 1 N sodium hydroxide and the solution is stirred at 40°-50° C. for 1 hour. The solution is acidified with 6 N hydrochloric acid to a pH of 7. Evaporation of the solvent gives the title compound in a 90% overall yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04236002 |
| 出典データセット | uspto-grants-1980_11 |
| ORD ID | ord-af841033f58e4f8598fea6d220f4ff2f |
| 出典メモ | uspto-grants-1980_11 |