Ethyl 3-(furan-2-yl)benzoate → [3-(2-Furyl)phenyl]methanol

HRID 2254439ノート

反応式

HRID 2254439 の反応式
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:7]=[C:8]([CH:14]=[CH:15][CH:16]=1)[C:9](OCC)=[O:10].[H-].[Al+3].[Li+].[H-].[H-].[H-]>C(OCC)C>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:7]=[C:8]([CH:14]=[CH:15][CH:16]=1)[CH2:9][OH:10]

参加物

4

反応物 2

HCID 19744763Ethyl 3-(furan-2-yl)benzoateHCID 21226445Aluminium lithium hydride

生成物 1

HCID 11116545[3-(2-Furyl)phenyl]methanol収率 83%

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

Ethyl 3-(2-furyl)benzoate J. Chem. Soc., (B), 1971, 2305] was dissolved in 5 ml of anhydrous ethyl ether, and with stirring under ice cooling, 23 mg of lithium aluminum hydride was added. The mixture was stirred for 40 minutes. After the reaction, the reaction mixture was extracted by adding water and ethyl ether. The extract was worked up in a customary manner to give 170 mg (yield 83%) of 3-(2-furyl)benzyl alcohol.

後処理

  1. stirringThe mixture was stirred for 40 minutes
  2. customAfter the reaction
  3. extractionthe reaction mixture was extracted
  4. additionby adding water and ethyl ether

出典と根拠

ORDレコード
ord-4554c789d62e45aebdcbd8fde12e3df5
出典データセット
uspto-grants-1993_08
特許番号
US05234946

反応ノート

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