Water → [3-(2-Furyl)phenyl]methanol

HRID 2254445ノート

反応式

HRID 2254445 の反応式
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:7]=[C:8]([CH:14]=[CH:15][CH:16]=1)[C:9](OCC)=[O:10].[H-].[Al+3].[Li+].[H-].[H-].[H-].O>C(OCC)C>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:7]=[C:8]([CH:14]=[CH:15][CH:16]=1)[CH2:9][OH:10]

参加物

5

反応物 3

HCID 962WaterHCID 19744763Ethyl 3-(furan-2-yl)benzoateHCID 21226445Aluminium lithium hydride

生成物 1

HCID 11116545[3-(2-Furyl)phenyl]methanol収率 83%

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒2 回

実験手順

Ethyl 3-(2-furyl)benzoate [J. Chem. Soc., (B), 1971, 2305 was dissolved in 5 ml of anhydrous ethyl ether. With stirring under ice cooling, 23 mg of lithium aluminium hydride was added The mixture was stirred for 40 minutes. After the reaction, water and ethyl ether were added to extract the reaction mixture The extract was worked up in a customary manner to give 170 mg (yield 83%) of 3-(2-furyl)benzyl alcohol

後処理

  1. stirringwas stirred for 40 minutes
  2. additionwere added
  3. extractionto extract the reaction mixture The extract

出典と根拠

ORDレコード
ord-04c96a60e1bb477194670d995865208b
出典データセット
uspto-grants-1993_08
特許番号
US05234946

反応ノート

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