化工社化工社 化学情報印刷レポート · 研究参考用
1-Bromooctane → N-(6-Methylthioquinolin-5-yl)-2-octanyl-1,3-dithiane-2-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Bromooctane | HCID 8140 | — |
| 反応物 | 1,3-Dithiane-2-carboxylic acid | HCID 303705 | — |
| 反応物 | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| 反応物 | 5-Amino-6-methylthioquinoline | HCID 10397660 | — |
| 反応物 | 2-Octanyl-1,3-dithiane-2-carboxylic acid | HCID 14995436 | — |
| 生成物 | N-(6-Methylthioquinolin-5-yl)-2-octanyl-1,3-dithiane-2-carboxamide | HCID 14995437 | — |
反応手順
5-Amino-6-methylthioquinoline, prepared as described in Example 34, was coupled with 2-octanyl-1,3-dithiane-2-carboxylic acid, prepared by treatment of 1,3-dithiane-2-carboxylic acid with sodium hexamethyldisilazide and octanyl bromide, according to Example 25 to give the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05656634 |
| 出典データセット | uspto-grants-1997_08 |
| ORD ID | ord-4d6c93e5e33d4516bc673bed9e497a14 |
| 出典メモ | uspto-grants-1997_08 |