化工社化工社 化学情報印刷レポート · 研究参考用
Beta-Alanine → rac-(1R,3S)-3-aminocyclohexane-1-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Beta-Alanine | HCID 239 | — |
| 反応物 | N,N,N-trimethylglycinium | HCID 248 | — |
| 反応物 | Guvacine | HCID 3532 | — |
| 反応物 | Nipecotic Acid | HCID 4498 | — |
| 反応物 | L-2,4-Diaminobutyric acid | HCID 134490 | — |
| 反応物 | HCID 178518980 | HCID 178518980 | — |
| 生成物 | rac-(1R,3S)-3-aminocyclohexane-1-carboxylic acid | HCID 7005079 | — |
反応手順
[3H]GABA3 (98.9 Ci/mmole) was obtained from New England Nuclear (Boston, Mass.). β-alanine, betaine and L-DABA (L-(2,4) diaminobutyric acid) were from Sigma Chemical Company (St. Louis, Mo.); guvacine, nipecotic acid, OH-nipecotic (hydroxynipecotic acid), and THPO (4,5,6,7-tetrahydroisoxazolo (4,5-c]pyridin-3-ol) were from RBI (Natick, Mass.). ACHC (cis-3-aminocyclohexanecarboxylic acid) was kindly provided by Drs. Richard Milius and William White of the NIgH Chemical Synthesis Program.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05658786 |
| 出典データセット | uspto-grants-1997_08 |
| ORD ID | ord-c3d8464b3e0f4cc59bc7a4ef77c0d2bc |
| 出典メモ | uspto-grants-1997_08 |