化工社化工社 化学情報印刷レポート · 研究参考用
ethyl 1-methyl-1H-indole-2-carboxylate → N,1-Dimethyl-5-fluoro-1H-indole-2-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | ethyl 1-methyl-1H-indole-2-carboxylate | HCID 143368 | — |
| 反応物 | Ethyl 5-fluoro-1-methyl-1H-indole-2-carboxylate | HCID 10775338 | — |
| 生成物 | N,1-Dimethyl-5-fluoro-1H-indole-2-carboxamide | HCID 22593743 | 68% |
反応手順
According to the procedure of Preparation 1(b), except substituting ethyl 5-fluoro-1-methyl-1H-indole-2-carboxylate for the ethyl 1-methyl-1H-indole-2-carboxylate, the title compound (2.1 g, 68%) was prepared as a white solid: MS (ES) m/e 207 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07557125B2 |
| 出典データセット | uspto-grants-2009_07 |
| ORD ID | ord-5937838202174a5190a842483394e586 |
| 出典メモ | uspto-grants-2009_07 |