1-Methylindole-2-carboxaldehyde → 3,4-Dimethyl-2-(methylaminomethyl)thieno[2,3-b]thiophene

HRID 225905

反応式

HRID 225905 の反応式
[CH3:1][C:2]1[C:9]2[C:8]([CH3:10])=[CH:7][S:6][C:5]=2[S:4][C:3]=1[CH:11]=O.[CH3:13][N:14]1C2C(=CC=CC=2)C=C1C=O>>[CH3:1][C:2]1[C:9]2[C:8]([CH3:10])=[CH:7][S:6][C:5]=2[S:4][C:3]=1[CH2:11][NH:14][CH3:13]

参加物

3

反応物 2

HCID 2671641-Methylindole-2-carboxaldehydeHCID 27787713,4-Dimethylthieno[2,3-B]Thiophene-2-Carbaldehyde

生成物 1

HCID 225937563,4-Dimethyl-2-(methylaminomethyl)thieno[2,3-b]thiophene収率 53%

実験手順

According to the procedure of Preparation 24(a), except substituting 3,4-dimethylthieno[2,3-b]thiophene-2-carboxaldehyde (0.5 g, 2.5 mmole) for the 1-methylindole-2-carboxaldehyde, the title compound (0.28 g, 53%) was prepared as a colorless oil: MS (ES) m/e 212 (M+H)+.

出典と根拠

ORDレコード
ord-2ed4e6cc15e7466c85d7d1c0f3c77dbb
出典データセット
uspto-grants-2009_07
特許番号
US07557125B2

関連ノート

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