Acrylamide → 3-[{2-(1,3-Benzodioxol-5-yl)ethyl}thio]propionamide
反応式
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][CH2:11][SH:12])=[CH:9][C:4]=2[O:3][CH2:2]1.[C:13]([NH2:17])(=[O:16])[CH:14]=[CH2:15]>C(O)C>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][CH2:11][S:12][CH2:15][CH2:14][C:13]([NH2:17])=[O:16])=[CH:9][C:4]=2[O:3][CH2:2]1参加物
4
実験手順
5 g of 2-(1,3-benzodioxol-5-yl)ethanethiol and 4 g of acrylamide were dissolved in 100 ml of ethanol and the solution was heated under reflux to conduct the reaction for 20 h. The reaction mixture was cooled with ice. 100 ml of ethanol was added thereto and crystals thus formed were recovered by filtration to obtain 4.2 g of the intended compound in the form of colorless needles.
後処理
- temperaturethe solution was heated
- temperatureunder reflux
- customthe reaction for 20 h
- temperatureThe reaction mixture was cooled with ice
- customcrystals thus formed
- filtrationwere recovered by filtration
出典と根拠
- ORDレコード
- ord-47aaf99627ea4e2093946d2b4eb65c62
- 出典データセット
- uspto-grants-1995_12
- 特許番号
- US05475024
反応ノート
読み込み中…