Thiourea → HCID 68428752、化合物
反応式
[Br:1][CH2:2][C:3]1[CH:12]=[CH:11][CH:10]=[CH:9][C:4]=1[C:5]([O:7][CH3:8])=[O:6].[NH2:13][C:14]([NH2:16])=[S:15]>CO>[BrH:1].[NH2:16][C:14](=[NH:13])[S:15][CH2:2][C:3]1[CH:12]=[CH:11][CH:10]=[CH:9][C:4]=1[C:5]([O:7][CH3:8])=[O:6]参加物
4
実験手順
A mixture of the crude bromide from Step 1 (7.2 g, 0.031 mmol) and thiourea (2.6 g, 35 mmol) in MeOH (40 mL) was heated to reflux for 4 h, cooled to room temperature, and concentrated to afford methyl 2-({[amino(imino)methyl]thio}methyl)benzoate hydrobromide (10 g, ca. 100%), which was used without purification.
後処理
- temperaturewas heated
- temperatureto reflux for 4 h
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-b44dfef5a5ee4568b7331c94f729811b
- 出典データセット
- uspto-grants-2009_07
- 特許番号
- US07557135B2
反応ノート
読み込み中…