HCID 19002173、化合物 → HCID 178438424、化合物
反応式
C1(C(C2C=CC=CC=2)(C2C=CC=CC=2)[N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[C:19]3[CH:24]=[CH:23][C:22]([CH2:25][N:26]4[N:30]5[N:31]=[C:32]([CH3:34])[N:33]=[C:29]5[C:28]([CH2:35][C:36]5[CH:41]=[CH:40][C:39]([C:42]6[CH:47]=[CH:46][CH:45]=[CH:44][C:43]=6[C:48]6[N:52](C(C7C=CC=CC=7)(C7C=CC=CC=7)C7C=CC=CC=7)[N:51]=[N:50][N:49]=6)=[CH:38][CH:37]=5)=[C:27]4[CH2:72][CH2:73][CH3:74])=[CH:21][CH:20]=3)=[N:11][N:10]=[N:9]2)C=CC=CC=1>C1(C)C=CC=CC=1>[NH:11]1[C:12]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:19]2[CH:20]=[CH:21][C:22]([CH2:25][N:26]3[N:30]4[N:31]=[C:32]([CH3:34])[N:33]=[C:29]4[C:28]([CH2:35][C:36]4[CH:41]=[CH:40][C:39]([C:42]5[CH:47]=[CH:46][CH:45]=[CH:44][C:43]=5[C:48]5[NH:49][N:50]=[N:51][N:52]=5)=[CH:38][CH:37]=4)=[C:27]3[CH2:72][CH2:73][CH3:74])=[CH:23][CH:24]=2)=[N:8][N:9]=[N:10]1参加物
3
実験手順
A 342 mg portion of 5,7-bis[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-2-methyl-6-propyl-5H-pyrazolo[1,5-b][1,2,4]triazole (compound 1a) was treated in the same manner as described in Example 12, the resulting residue was mixed with toluene and heated under reflux and then the solution was cooled spontaneously to collect the thus formed precipitate by filtration, thereby giving 182 mg of 5,7-bis[[2'-(tetrazol-5-yl)biphenyl-4-yl]methyl]-2-methyl- 6-propyl-5H-pyrazolo[1,5-b][1,2,4]triazole in the form of colorless amorphous solid.
後処理
- temperatureheated