HCID 19002116、化合物 → HCID 19002116、化合物
反応式
[CH2:1]([O:3][C:4]1[CH:11]=[C:10]2[N:6]([N:7]=[C:8]([CH2:49][CH3:50])[N:9]2CC2C=CC(C3C=CC=CC=3C3N(C(C4C=CC=CC=4)(C4C=CC=CC=4)C4C=CC=CC=4)N=NN=3)=CC=2)[N:5]=1)[CH3:2].[CH2:51]([O:53][C:54]1[N:55]([CH2:64][C:65]2[CH:70]=[CH:69][C:68]([C:71]3[CH:76]=[CH:75][CH:74]=[CH:73][C:72]=3[C:77]3[N:81]([C:82]([C:95]4[CH:100]=[CH:99][CH:98]=[CH:97][CH:96]=4)([C:89]4[CH:94]=[CH:93][CH:92]=[CH:91][CH:90]=4)[C:83]4[CH:88]=[CH:87][CH:86]=[CH:85][CH:84]=4)[N:80]=[N:79][N:78]=3)=[CH:67][CH:66]=2)[N:56]2[C:60]([CH:61]=1)=[N:59][C:58]([CH2:62][CH3:63])=[N:57]2)[CH3:52]>>[CH2:51]([O:53][C:54]1[N:55]([CH2:64][C:65]2[CH:66]=[CH:67][C:68]([C:71]3[CH:76]=[CH:75][CH:74]=[CH:73][C:72]=3[C:77]3[N:81]([C:82]([C:83]4[CH:88]=[CH:87][CH:86]=[CH:85][CH:84]=4)([C:95]4[CH:96]=[CH:97][CH:98]=[CH:99][CH:100]=4)[C:89]4[CH:90]=[CH:91][CH:92]=[CH:93][CH:94]=4)[N:80]=[N:79][N:78]=3)=[CH:69][CH:70]=2)[N:56]2[C:60]([CH:61]=1)=[N:59][C:58]([CH2:62][CH3:63])=[N:57]2)[CH3:52].[CH2:1]([O:3][C:4]1[CH:11]=[C:10]2[N:6]([N:7]=[C:8]([CH2:49][CH3:50])[NH:9]2)[N:5]=1)[CH3:2]参加物
4
実験手順
In the same manner as described in Example 66, 1.02 g of 6-ethoxy-2-ethyl-1-[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-pyrazolo[1,5-b][1,2,4]triazole (compound 77a) and 1.22 g of 6-ethoxy-2-ethyl-5-[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-5H-pyrazolo[1,5-b][1,2,4]triazole (compound 77b) were obtained from 1.80 g of 6-ethoxy-2-ethyl-1H-pyrazolo[1,5-b][1,2,4]triazole.