Potassium Hydroxide → N-(2,3-dihydroxypropyl)-N-tetradecyl-2-hydroxyhexadecanamide

HRID 2260093

反応式

HRID 2260093 の反応式
[OH:1][CH:2]([CH2:19][OH:20])[CH2:3][NH:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[OH-].[K+].[OH:23][CH:24]([CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[C:25]([O:27]C)=O>>[OH:1][CH:2]([CH2:19][OH:20])[CH2:3][N:4]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[C:25](=[O:27])[CH:24]([OH:23])[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42]

参加物

4

反応物 3

HCID 14797Potassium HydroxideHCID 543716Methyl 2-hydroxyhexadecanoateHCID 189993733-(Tetradecylamino)propane-1,2-diol

生成物 1

HCID 15825479N-(2,3-dihydroxypropyl)-N-tetradecyl-2-hydroxyhexadecanamide

実験手順

N-(2,3-dihydroxypropyl)-N-tetradecylamine (1.00 g, 0.0035 mole) and potassium hydroxide (0.01 g, 0.18 mmole) were heated to 85° C. under vacuum and methyl 2-hydroxyhexadecanoate (0.94 g, 0.0035 mole) was heated and added dropwise to the reaction. The reaction was heated under vacuum for 6 hours. A waxy off-white solid was obtained (crude yield=1.8 g). The waxy solid was recrystalized from hot hexane (yield=1.09 g)

後処理

  1. temperaturewas heated
  2. additionadded dropwise to the reaction
  3. temperatureThe reaction was heated under vacuum for 6 hours
  4. customA waxy off-white solid was obtained (crude yield=1.8 g)
  5. customThe waxy solid was recrystalized from hot hexane (yield=1.09 g)

出典と根拠

ORDレコード
ord-c1472dca73cd46df91a58f0a72ee7414
出典データセット
uspto-grants-1995_12
特許番号
US05476671

関連ノート

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