化工社化工社 化学情報印刷レポート · 研究参考用
1H-Indazole-5,6-diamine → 6-thienyl-1H-pyrazolo[3,4-g]quinoxaline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1H-Indazole-5,6-diamine | HCID 81900 | — |
| 反応物 | 2-Oxo-2-(thiophen-2-yl)acetaldehyde | HCID 5272214 | — |
| 生成物 | 6-thienyl-1H-pyrazolo[3,4-g]quinoxaline | HCID 18999799 | — |
| 生成物 | 7-thienyl-1H-pyrazolo[3,4-g]quinoxaline | HCID 18999807 | — |
反応手順
Condensation as shown in Step A of 5,6-diaminoindazole with a glyoxyloylthiophene in the presence of absolute alcohol results in ring formation of a mixture of 6-thienyl-1H-pyrazolo[3,4-g]quinoxaline and 7-thienyl-1H-pyrazolo[3,4-g]quinoxaline. These positional isomers can be separated by standard procedures, such as column chromatography.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05476851 |
| 出典データセット | uspto-grants-1995_12 |
| ORD ID | ord-ff16d6430b4b4a79a0159c115bd9bafd |
| 出典メモ | uspto-grants-1995_12 |