1H-Indazole-5,6-diamine → 6-(5-chlorothien-2-yl)-1H-pyrazolo[3,4-g]quinoxaline 7-(5-chlorothien-2-yl)-1H-pyrazolo[3,4-g]quinoxaline

HRID 2260110

反応式

HRID 2260110 の反応式
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[NH2:11])[NH:7][N:6]=[CH:5]2.[Cl:12][C:13]1[S:14][C:15]([C:18](=O)[CH:19]=O)=[CH:16][CH:17]=1>C(O)C>[Cl:12][C:13]1[S:14][C:15]([C:18]2[CH:19]=[N:1][C:2]3[CH:3]=[C:4]4[CH:5]=[N:6][NH:7][C:8]4=[CH:9][C:10]=3[N:11]=2)=[CH:16][CH:17]=1.[Cl:12][C:13]1[S:14][C:15]([C:18]2[CH:19]=[N:11][C:10]3[CH:9]=[C:8]4[NH:7][N:6]=[CH:5][C:4]4=[CH:3][C:2]=3[N:1]=2)=[CH:16][CH:17]=1

参加物

4

反応物 2

HCID 819001H-Indazole-5,6-diamineHCID 187887102-Chloro-5-glyoxyloylthiophene

生成物 1

HCID 189998206-(5-chlorothien-2-yl)-1H-pyrazolo[3,4-g]quinoxaline 7-(5-chlorothien-2-yl)-1H-pyrazolo[3,4-g]quinoxaline

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒2 回

実験手順

To a mixture of 5,6-diaminoindazole (0.5 g) in 30 ml absolute ethanol is added slowly a solution of 2-chloro-5-glyoxyloylthiophene (0.72 g) and 20 ml ethanol. The resulting mixture is stirred at room temperature for 4.5 hours. The yellow solid which forms is filtered off, washed with ethanol then with hexane and air dried overnight.

後処理

  1. filtrationThe yellow solid which forms is filtered off
  2. washwashed with ethanol
  3. dry with materialwith hexane and air dried overnight

出典と根拠

ORDレコード
ord-5922bbc9349b42c8bc5ca660f6846243
出典データセット
uspto-grants-1995_12
特許番号
US05476851

関連ノート

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