[5-(Propan-2-yl)-1,2-oxazol-3-yl]methanol → 5-(Propan-2-yl)-1,2-oxazole-3-carbaldehyde
反応式
[CH:1]([C:4]1[O:8][N:7]=[C:6]([CH2:9][OH:10])[CH:5]=1)([CH3:3])[CH3:2]>O1CCOCC1.[O-2].[O-2].[Mn+4]>[CH:1]([C:4]1[O:8][N:7]=[C:6]([CH:9]=[O:10])[CH:5]=1)([CH3:3])[CH3:2]参加物
4
実験手順
7.59 g of (5-i-propyl-isoxazol-3-yl)methanol was dissolved in 100 ml of 1,4-dioxane, and 21.74 g of manganese dioxide was then added. The mixture was stirred and heated under reflux for 10 hours. The reaction mixture was cooled to room temperature and then filtered through Celite®. The filtrate was concentrated under reduced pressure to obtain 6.72 g of 5-i-propyl-isoxazole-3-carbaldehyde.
後処理
- temperatureheated
- temperatureunder reflux for 10 hours
- filtrationfiltered through Celite®
- concentrationThe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-4bcacf6a2d234571bddd39f6c003316d
- 出典データセット
- uspto-grants-2010_12
- 特許番号
- US07846956B2
反応ノート
読み込み中…