Dichloromethane → HCID 73989400、化合物
反応式
[C:1]1([NH:7][S:8]([C:11]2[CH:16]=[CH:15][C:14]([CH:17]=[CH:18][C:19]([OH:21])=O)=[CH:13][CH:12]=2)(=[O:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:22]CCl>CN(C)C=O>[C:1]1([NH:7][S:8]([C:11]2[CH:16]=[CH:15][C:14]([CH:17]=[CH:18][C:19]([Cl:22])=[O:21])=[CH:13][CH:12]=2)(=[O:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
4
反応条件
- 温度
- 40 °C
実験手順
To a suspension of 3-(4-phenylsulfamoyl-phenyl)-acrylic acid (43a) (0.25 g, 0.82 mmol) in dichloromethane (4.7 ml) oxalyl chloride (0.32 ml, 3.68 mmol) and one drop of dimethylformamide were added. The reaction mixture was stirred at 40° C. for one hour and concentrated under reduced pressure to give crude title compound (0.24 g, 92%).
後処理
- additionwere added
- concentrationconcentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-fb988d1bea7f4047945bbbaea2bf1e45
- 出典データセット
- uspto-grants-2009_07
- 特許番号
- US07557140B2
反応ノート
読み込み中…