2-(4-Methoxy-phenyl)-benzo[b]thiophene-6-carboxylic acid methyl ester → 2-(4-Hydroxy-phenyl)-benzo[b]thiophene-6-carboxylic Acid Methyl Ester

HRID 2261771ノート

反応式

HRID 2261771 の反応式
C(OC(C1SC(C2C=CC(O)=CC=2)=NC=1C)=O)C.[CH3:19][O:20][C:21]([C:23]1[CH:24]=[CH:25][C:26]2[CH:30]=[C:29]([C:31]3[CH:36]=[CH:35][C:34]([O:37]C)=[CH:33][CH:32]=3)[S:28][C:27]=2[CH:39]=1)=[O:22]>>[CH3:19][O:20][C:21]([C:23]1[CH:24]=[CH:25][C:26]2[CH:30]=[C:29]([C:31]3[CH:36]=[CH:35][C:34]([OH:37])=[CH:33][CH:32]=3)[S:28][C:27]=2[CH:39]=1)=[O:22]

参加物

3

反応物 2

HCID 574432832-(4-Methoxy-phenyl)-benzo[b]thiophene-6-carboxylic acid methyl esterHCID 135509402Ethyl 2-(4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate

生成物 1

HCID 179625242-(4-Hydroxy-phenyl)-benzo[b]thiophene-6-carboxylic Acid Methyl Ester収率 12%

実験手順

The title compound (57 mg, 12%) is prepared essentially according to the preparation of 2-(4-Hydroxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester using 2-(4-methoxy-phenyl)-benzo[b]thiophene-6-carboxylic acid methyl ester. LC-ES/MS m/e 283 (M−1).

出典と根拠

ORDレコード
ord-e571cf2f7e6844e380e617cff73a106d
出典データセット
uspto-grants-2010_12
特許番号
US07846960B2

反応ノート

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