Methyl 4-methoxy-2-methylbenzoate → Methyl 4-hydroxy-2-methylbenzoate

反応式

COC(=O)C1C=C(O)C=CC=1CCC.[CH3:15][O:16][C:17](=[O:27])[C:18]1[CH:23]=[CH:22][C:21]([O:24]C)=[CH:20][C:19]=1[CH3:26]>>[CH3:15][O:16][C:17](=[O:27])[C:18]1[CH:23]=[CH:22][C:21]([OH:24])=[CH:20][C:19]=1[CH3:26]

参加物

反応物 2

HCID 13257269Methyl 4-methoxy-2-methylbenzoate

HCID 57443304HCID 57443304、化合物

生成物 1

HCID 12351986Methyl 4-hydroxy-2-methylbenzoate収率 77%

実験手順

The title compound (77%) is prepared essentially according to the preparation of 5-hydroxy-2-propyl-benzoic acid methyl ester using 4-methoxy-2-methyl-benzoic acid methyl ester. 1H NMR (400 MHz, CDCl3) δ 7.91-7.86 (m, 1H), 6.72-6.67 (m, 2H), 3.86 (s, 3H), 2.57 (s, 3H).

出典と根拠

ORDレコード: ord-4dc682541de245f98e0ec8773c14bce9
出典データセット: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07846960B2

反応ノート

読み込み中…