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Benzoyl Peroxide → Methyl 3-(bromomethyl)benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoyl Peroxide | HCID 7187 | — |
| 反応物 | Benzoic acid, 3-methyl-, methyl ester | HCID 7435 | — |
| 反応物 | N-bromobutanimide | HCID 67184 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 生成物 | Methyl 3-(bromomethyl)benzoate | HCID 517981 | — |
反応手順
A mixture of 5.5 g (36 mmol) of methyl 3-methylbenzoate, 7.1 g (39.5 mmol) of N-Bromosuccinimide and 0.44 g (1.8 mmol) of benzoyl peroxide in 75 ml of Cl4C is refluxed for 5 h. The solid is filtered and washed with Cl4C. The mother liquors are concentrated and a yellow solid is obtained which is, essentially, monobromated product. This is used in the next step without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07557212B2 |
| 出典データセット | uspto-grants-2009_07 |
| ORD ID | ord-be0a5fcfdd5242d0a7929c42ccb8756c |
| 出典メモ | uspto-grants-2009_07 |