Aluminium lithium hydride → (2R,6S)-1-ethyl-2,6-dimethylpiperazine

反応式

[C:1]([N:4]1[C@@H:9]([CH3:10])[CH2:8][NH:7][CH2:6][C@H:5]1[CH3:11])(=O)[CH3:2].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:1]([N:4]1[C@@H:9]([CH3:10])[CH2:8][NH:7][CH2:6][C@H:5]1[CH3:11])[CH3:2]

参加物

反応物 2

HCID 21226445Aluminium lithium hydride

HCID 228390341-[(2R,6S)-2,6-Dimethylpiperazin-1-yl]ethan-1-one

生成物 1

HCID 28363792(2R,6S)-1-ethyl-2,6-dimethylpiperazine

実験手順

(2R,6S)-1-Acetyl-2,6-dimethylpiperazine was reduced with lithium aluminum hydride to obtain (2R,6S)-1-ethyl-2,6-dimethylpiperazine.

出典と根拠

ORDレコード: ord-28639cf5e79742cbab7c80848e18092b
出典データセット: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07855198B2

反応ノート

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