化工社化工社 化学情報印刷レポート · 研究参考用
(4-Fluoro-3-methoxyphenyl)boronic acid → 2-[5-(4-Fluoro-3-methoxy-phenoxy)-4'-trifluoromethyl-biphenyl-3-yl]-4-methyl-pentanoic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (4-Fluoro-3-methoxyphenyl)boronic acid | HCID 44558185 | — |
| 反応物 | 2-(5-Hydroxy-4'-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester | HCID 57754941 | — |
| 生成物 | 2-[5-(4-Fluoro-3-methoxy-phenoxy)-4'-trifluoromethyl-biphenyl-3-yl]-4-methyl-pentanoic acid methyl ester | HCID 57754920 | 30% |
反応手順
The title compound was prepared in 30% yield from 2-(5-hydroxy-4′-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester and 4-fluoro-3-methoxyphenylboronic acid under the conditions described in Example 15, step (g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07557244B2 |
| 出典データセット | uspto-grants-2009_07 |
| ORD ID | ord-f831beafbbb943c7aeb9058f9ecbb984 |
| 出典メモ | uspto-grants-2009_07 |