化工社化工社 化学情報印刷レポート · 研究参考用
3-Amino-5-fluorobenzotrifluoride → 2-[4'-Chloro-5-(3-fluoro-5-trifluoromethyl-phenylamino)-3'-trifluoromethyl-biphenyl-3-yl]-4-methyl-pentanoic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Amino-5-fluorobenzotrifluoride | HCID 2735913 | — |
| 反応物 | 2-(4'-Chloro-5-trifluoromethanesulfonyloxy-3'-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester | HCID 57754964 | — |
| 生成物 | 2-[4'-Chloro-5-(3-fluoro-5-trifluoromethyl-phenylamino)-3'-trifluoromethyl-biphenyl-3-yl]-4-methyl-pentanoic acid methyl ester | HCID 57755005 | 28% |
反応手順
The title compound was prepared in 28% yield from 2-(4′-chloro-5-trifluoromethanesulfonyloxy-3′-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester and 3-fluoro-5-(trifluoromethyl)aniline under the conditions described in Example 37, step (b). Mass spectrum (ES-, m/z): 560, 562 (M−H);
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07557244B2 |
| 出典データセット | uspto-grants-2009_07 |
| ORD ID | ord-5bd264eeef9d415dbff4b38bb0b2fed6 |
| 出典メモ | uspto-grants-2009_07 |