Butanethioic acid, 3-oxo-, S-(1,1-dimethylethyl) ester → 2-(2-chloro-4-methanesulfonylbenzyl)-3-oxothiobutyric acid S-tert-butyl Ester

反応式

Br[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH3:12])(=[O:11])=[O:10])=[CH:5][C:4]=1[Cl:13].[C:14]([S:18][C:19](=[O:24])[CH2:20][C:21](=[O:23])[CH3:22])([CH3:17])([CH3:16])[CH3:15]>>[C:14]([S:18][C:19](=[O:24])[CH:20]([CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH3:12])(=[O:11])=[O:10])=[CH:5][C:4]=1[Cl:13])[C:21](=[O:23])[CH3:22])([CH3:17])([CH3:15])[CH3:16]

参加物

反応物 2

HCID 140007Butanethioic acid, 3-oxo-, S-(1,1-dimethylethyl) ester

HCID 27610831-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene

生成物 1

HCID 866314412-(2-chloro-4-methanesulfonylbenzyl)-3-oxothiobutyric acid S-tert-butyl Ester

実験手順

The title compound was prepared by the method of Preparation 34a using 1-bromomethyl-2-chloro-4-methanesulfonylbenzene and 3-oxothiobutyric acid S-tert-butyl ester

出典と根拠

ORDレコード: ord-6b2f8d785a4b4b709bf464b2bf022b06
出典データセット: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07858640B2

反応ノート

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