4-(4-Chlorophenyl)-1-[3-(5,11-dihydro-7-hydroxy [1]benzoxepino [2,3-b]pyridin-5-ylidene)propyl]piperidin-4-ol → 4-(4-Chlorophenyl)-1-[3-(5,11-dihydro-7-ethoxy[1]benzoxepino[2,3-b]pyridin-5-ylidene)propyl]piperidine
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2(O)[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH:16]=[C:17]3[C:27]4[C:22](=[N:23][CH:24]=[CH:25][CH:26]=4)[O:21][C:20]4[CH:28]=[CH:29][CH:30]=[C:31]([OH:32])[C:19]=4[CH2:18]3)[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.Cl[C:35]1C=CC(C2CCN(CCC=C3C4C(=NC=CC=4)OC4C=CC=C(O)C=4C3)CC2)=C[CH:36]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][CH:16]=[C:17]3[C:27]4[C:22](=[N:23][CH:24]=[CH:25][CH:26]=4)[O:21][C:20]4[CH:28]=[CH:29][CH:30]=[C:31]([O:32][CH2:35][CH3:36])[C:19]=4[CH2:18]3)[CH2:12][CH2:13]2)=[CH:6][CH:7]=1参加物
3
反応物 2
生成物 1
実験手順
The titled compound was prepared by following the procedure of example 46, but replacing the product of example 44 with the product of example 151.