化工社化工社 化学情報印刷レポート · 研究参考用
3-Fluoroaniline → HCID 178500755、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Fluoroaniline | HCID 9742 | — |
| 反応物 | 2-(3,4-Dimethyl-benzoyl)-3-methoxy-acrylic acid methyl ester | HCID 66879272 | — |
| 反応物 | HCID 178500760 | HCID 178500760 | — |
| 生成物 | HCID 178500755 | HCID 178500755 | 50.1% |
反応手順
Compound 2h was prepared following the procedure described in Step 1 of Example 1 using from 2g (8.06 mmol) of crude 2-(3,4-Dimethyl-benzoyl)-3-methoxy-acrylic acid methyl ester 1a and 0.806 g (7.26 mmol) 3-fluoroaniline. The crude product 2h was purified by recrystalization with dichloromethane/hexane to yield 1.19 g of 2-(3,4-Dimethyl-benzoyl)-3-(3-fluoro-phenylamino)-acrylic acid methyl ester as a brown solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07557213B2 |
| 出典データセット | uspto-grants-2009_07 |
| ORD ID | ord-19c6e3c0780148ec87451d8ba239704c |
| 出典メモ | uspto-grants-2009_07 |