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Cvt-2738 → 2-{4-[2-hydroxy-3-(2-methyl-benzothiazol-5-yloxy)-propyl]-piperazin-1-yl}-N-(4-hydroxy-phenyl)acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cvt-2738 | HCID 2608606 | — |
| 反応物 | 2-Methyl-5-(oxiran-2-ylmethoxy)benzothiazole | HCID 9920872 | — |
| 反応物 | HCID 20754888 | HCID 20754888 | — |
| 生成物 | 2-{4-[2-hydroxy-3-(2-methyl-benzothiazol-5-yloxy)-propyl]-piperazin-1-yl}-N-(4-hydroxy-phenyl)acetamide | HCID 10276097 | — |
反応手順
Compound 54 was prepared in the manner of compound 7 substituting compound 33 for compound 6 and compound 57 for compound 5 in part D of compound 7: Mass Spectrum (MH+)=457.5.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06849632B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-033fbce828fd4fa496b7f4b0f867fdad |
| 出典メモ | uspto-grants-2005_02 |