化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → 2-(Tetrahydro-2H-pyran-4-yl)ethyl methanesulfonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Methanesulfonyl chloride | HCID 31297 | — |
| 反応物 | 2-(Oxan-4-yl)ethan-1-ol | HCID 17750944 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 2-(Tetrahydro-2H-pyran-4-yl)ethyl methanesulfonate | HCID 22273083 | — |
反応手順
The product of Example 8A (2.9 mmol), triethylamine (1.2 mL, 8.7 mmol) and methanesulfonyl chloride (0.34 mL, 4.4 mmol) in 10 mL tetrahydrofuran (THF) were reacted and the product isolated as in Example 1C to give the title compound that was used directly in the next reaction.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07560481B2 |
| 出典データセット | uspto-grants-2009_07 |
| ORD ID | ord-cab984eb0dbd4e83a9687a4e09548263 |
| 出典メモ | uspto-grants-2009_07 |