Quinoxaline-5-carbaldehyde → (S)-1,1-diethoxy-N-(quinoxalin-5-ylmethyl)propan-2-amine
反応式
[CH2:1]([O:3][CH:4]([O:8][CH2:9][CH3:10])[C@@H:5]([NH2:7])[CH3:6])[CH3:2].[N:11]1[C:20]2[CH:19]=[CH:18][CH:17]=[C:16]([CH:21]=O)[C:15]=2[N:14]=[CH:13][CH:12]=1>>[CH2:1]([O:3][CH:4]([O:8][CH2:9][CH3:10])[C@@H:5]([NH:7][CH2:21][C:16]1[CH:17]=[CH:18][CH:19]=[C:20]2[C:15]=1[N:14]=[CH:13][CH:12]=[N:11]2)[CH3:6])[CH3:2]参加物
3
実験手順
According to the procedure described in the synthesis method of Compound IX-6, (S)-1,1-diethoxypropan-2-amine (Compound XVIII-1) (1.57 g, 10.0 mmol) was reacted with quinoxaline-5-carbaldehyde (1.34 g, 8.5 mmol) to obtain the title compound (1.93 g, 78%).
出典と根拠
- ORDレコード
- ord-b5f6afd63d1041b191d05444cc01e469
- 出典データセット
- uspto-grants-2015_09
- 特許番号
- US09126981B2
反応ノート
読み込み中…