2-Methyl-2-(4-vinylphenyl)propanoic acid → 2-(4-Ethylphenyl)-2-methylpropanoic acid
反応式
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]([CH3:14])([CH3:13])[C:10]([OH:12])=[O:11])=[CH:5][CH:4]=1)=[CH2:2]>C(O)C.[C].[Pd]>[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]([CH3:13])([CH3:14])[C:10]([OH:12])=[O:11])=[CH:5][CH:4]=1)[CH3:2]参加物
4
実験手順
2-(4-Vinylphenyl)-2-methylpropanoic acid (58 g) was dissolved in ethanol, and then stirred for 3 hrs under atmospheric hydrogen pressure in the presence of 10% palladium carbon (5.8 g). The catalyst was removed by filtration, and the filtrate was concentrated to obtain a crude product, which was then suspended and washed with hexane to give the title compound (56.5 g, 94.8%).
後処理
- customThe catalyst was removed by filtration
- concentrationthe filtrate was concentrated
- customto obtain a crude product, which
- washwashed with hexane
出典と根拠
- ORDレコード
- ord-d35939d3b4eb4431b818bd9612521175
- 出典データセット
- uspto-grants-2015_09
- 特許番号
- US09126931B2
反応ノート
読み込み中…