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2-Aminothiazole → HCID 53255816、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Aminothiazole | HCID 2155 | — |
| 反応物 | 3-Pentanol | HCID 11428 | — |
| 反応物 | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| 反応物 | 2-(Pentan-3-yloxy)aniline | HCID 17605461 | — |
| 生成物 | HCID 53255816 | HCID 53255816 | 70% |
| 生成物 | N-[2-(3-pentoxy)phenyl]-N'-(thiazol-2-yl)urea | HCID 59732864 | 57% |
反応手順
2-(3-Pentoxy)-1-nitrobenzene (366 mg, 70%) was prepared from 3-pentanol (0.27 ml, 2.5 mmol) and 1-fluoro-2-nitrobenzene (0.36 g, 2.5 mmol) following the general procedure G. This was reduced to 2-(3-pentoxy)aniline (0.25 g, 80%) following general procedure B. N-[2-(3-pentoxy)phenyl]-N′-(thiazol-2-yl)urea (0.26 g, 57%) was prepared from 2-(3-pentoxy)-aniline (0.25 g, 1.5 mmol) and 2-aminothiazole (150 mg, 1.5 mmol) following the general procedure D.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | USRE045670E1 |
| 出典データセット | uspto-grants-2015_09 |
| ORD ID | ord-c7faffa6edaa4559af6d7e8a80e2656e |
| 出典メモ | uspto-grants-2015_09 |