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HRID 2278作成日：2026年10月23日

Benzaldehyde → 4-tert-butyl-N-[6-{2-(5-(alpha-hydroxybenzyl)primidin-2-yloxy)ethoxy}-5-(4-methylphenyl)pyrimidin-4-yl]-benzenesulfonamide

https://huagongshe.com/ja/reaction/2278

反応式

関与物質

役割名称HCID仕込み量
反応物BenzaldehydeHCID 240—
反応物4-tert-butyl-N-{6-[2-(5-bromopyrimidin-2-yloxy)ethoxy]-5-(4-methylphenyl)pyrimidin-4-yl}benzenesulfonamideHCID 9938571—
生成物4-tert-butyl-N-[6-{2-(5-(alpha-hydroxybenzyl)primidin-2-yloxy)ethoxy}-5-(4-methylphenyl)pyrimidin-4-yl]-benzenesulfonamideHCID 131719757—

反応手順

N-[6-{2-(5-Bromopyrimidin-2-yloxy)ethoxy}-5-(4-methylphenyl)pyrimidin-4-yl]-4-tert-butylbenzenesulfonamide and benzaldehyde are treated in the same manner as in Example 129 to give 4-tert-butyl-N-[6-{2-(5-(α-hydroxybenzyl)primidin-2-yloxy)ethoxy}-5-(4-methylphenyl)pyrimidin-4-yl]-benzenesulfonamide.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05728706
出典データセットuspto-grants-1998_03
ORD IDord-8cd0277d133e4a558c95fad0e057819e
出典メモuspto-grants-1998_03