化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl Acetate → (2-Methylpyrimidin-5-yl)methanamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl Acetate | HCID 8857 | — |
| 反応物 | 5-(Azidomethyl)-2-methylpyrimidine | HCID 54595022 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 生成物 | (2-Methylpyrimidin-5-yl)methanamine | HCID 21294601 | — |
反応手順
A mixture of 5-(azidomethyl)-2-methylpyrimidine (55 mg, 0.00037 mol) in ethyl acetate (20 mL, 0.2 mol), and 10% Pd—C (70 mg) was stirred under H2 (1 atm) for 2 hr. The catalyst was filtered off and filtrate was concentrated in vacuo to afford a white solid. LC/MS m/e 124.3 (M+H+)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09133122B2 |
| 出典データセット | uspto-grants-2015_09 |
| ORD ID | ord-ba85c4aa834c45a2993f12ffeb93fcd4 |
| 出典メモ | uspto-grants-2015_09 |