Benzene → (S)-tert-butyl 5-((S)-(2-fluoro-4-(trifluoromethyl)phenyl)(2-(tetrahydro-2H-pyran-4-ylamino)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxamido)methyl)-2,2-dimethylpyrrolidine-1-carboxylate

反応式

[C:1]([O:5][C:6]([N:8]1[C:12]([CH3:14])([CH3:13])[CH2:11][CH2:10][C@H:9]1[C@H:15]([C:19]1[CH:24]=[CH:23][C:22]([C:25]([F:28])([F:27])[F:26])=[CH:21][C:20]=1[F:29])C(O)=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].C1C=CC=CC=1.C1(P(N=[N+]=[N-])(C2C=CC=CC=2)=O)C=CC=CC=1.[O:53]1[CH2:58][CH2:57][CH:56]([NH:59][C:60]2[N:61]=[CH:62][C:63]3[CH2:69][CH2:68][NH:67][CH2:66][C:64]=3[N:65]=2)[CH2:55][CH2:54]1.C[N:71]([CH:73]=[O:74])C>O>[F:29][C:20]1[CH:21]=[C:22]([C:25]([F:26])([F:27])[F:28])[CH:23]=[CH:24][C:19]=1[C@H:15]([NH:71][C:73]([N:67]1[CH2:68][CH2:69][C:63]2[CH:62]=[N:61][C:60]([NH:59][CH:56]3[CH2:55][CH2:54][O:53][CH2:58][CH2:57]3)=[N:65][C:64]=2[CH2:66]1)=[O:74])[C@H:9]1[N:8]([C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:7])[C:12]([CH3:14])([CH3:13])[CH2:11][CH2:10]1