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1-benzyl-N-methylpiperidin-4-amine → 2-(5-amino-4,6-diisopropylpyrimidine-2-yloxy)-N-(1-benzylpiperidine-4-yl)-N-methylacetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-benzyl-N-methylpiperidin-4-amine | HCID 4136128 | — |
| 反応物 | Ethyl 2-(5-amino-4,6-diisopropylpyrimidine-2-yloxy)acetate | HCID 59336100 | — |
| 生成物 | 2-(5-amino-4,6-diisopropylpyrimidine-2-yloxy)-N-(1-benzylpiperidine-4-yl)-N-methylacetamide | HCID 59336117 | — |
反応手順
As in Example 11, a carboxylic acid derivative was synthesized from Compound 13. Then, the title compound was synthesized from the obtained carboxylic acid derivative and 1-benzyl-N-methylpiperidine-4-amine in the same manner as in Example 49.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09139559B2 |
| 出典データセット | uspto-grants-2015_09 |
| ORD ID | ord-ccc715b7e52947c69952351a6e31fb4f |
| 出典メモ | uspto-grants-2015_09 |