戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 2280938作成日：2026年10月26日

1-(cyclopropylmethyl)-N-methylpiperidine-4-amine → 2-(5-amino-4,6-diisopropylpyrimidine-2-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylacetamide

https://huagongshe.com/reaction/2280938

反応式

関与物質

役割名称HCID仕込み量
反応物1-(cyclopropylmethyl)-N-methylpiperidine-4-amineHCID 43314908—
反応物Ethyl 2-(5-amino-4,6-diisopropylpyrimidine-2-yloxy)acetateHCID 59336100—
生成物2-(5-amino-4,6-diisopropylpyrimidine-2-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylacetamideHCID 59336132—

反応手順

As in Example 11, a carboxylic acid derivative was synthesized from Compound 13. Then, the title compound was synthesized from the obtained carboxylic acid derivative and 1-(cyclopropylmethyl)-N-methylpiperidine-4-amine in the same manner as in Example 49.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09139559B2
出典データセットuspto-grants-2015_09
ORD IDord-8e9161ce00564daa98984cf0ea6077aa
出典メモuspto-grants-2015_09