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2-Amino-4-methylpyrimidine → cyclohexyl-[7-methyl-2-(1-methyl-1H-pyrrol-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Amino-4-methylpyrimidine | HCID 7939 | — |
| 反応物 | 1-Methyl-1H-pyrrole-2-carbaldehyde | HCID 14504 | — |
| 反応物 | Cyclohexyl isocyanide | HCID 79129 | — |
| 溶媒 | Perchloric Acid | HCID 24247 | — |
| 生成物 | cyclohexyl-[7-methyl-2-(1-methyl-1H-pyrrol-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-amine | HCID 22591929 | — |
反応手順
Compound (38) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-4-methylpyrimidine solution (0.1 M, DCM), 0.575 ml of cyclohexyl isocyanide solution (0.2 M, DCM), 0.500 ml of N-methylpyrrole-2-carbaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06849642B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-9a13c14e378f4b7cabd9e4ac51904452 |
| 出典メモ | uspto-grants-2005_02 |