Ammonium Hydroxide → 5-ethyl-1-methyl-1H-pyrazole-3-carboxamide
反応式
[CH2:1]([C:3]1[N:7]([CH3:8])[N:6]=[C:5]([C:9]([O:11]CC)=O)[CH:4]=1)[CH3:2].[OH-].[NH4+:15]>>[CH2:1]([C:3]1[N:7]([CH3:8])[N:6]=[C:5]([C:9]([NH2:15])=[O:11])[CH:4]=1)[CH3:2]参加物
3
実験手順
A mixture of ethyl 5-ethyl-1-methyl-1H-pyrazole-3-carboxylate (5.03 g, 27.6 mmol) and ammonium hydroxide (28 mL of 30%) was stirred for 18 hours at ambient temperature. A precipitate formed, was isolated by filtration, and washed with cold hexanes to provide 2.60 g of 5-ethyl-1-methyl-1H-pyrazole-3-carboxamide as a white solid, mp 170-172° C.
後処理
- customA precipitate formed
- customwas isolated by filtration
- washwashed with cold hexanes
出典と根拠
- ORDレコード
- ord-0b90539ce36944738213eb0734ab4bd5
- 出典データセット
- uspto-grants-2015_09
- 特許番号
- US09145410B2
反応ノート
読み込み中…