4-(4-Cyclopropanecarbonylpiperazino)benzoate → N-(1-(4-Cyclopropanecarboxamidophenyl)-1H-indazol-5-yl)-4-(4-cyclopropanecarbonylpiperazino)benzamide
反応式
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:16]=[CH:15][C:14]([NH2:17])=[CH:13][CH:12]=1)[N:6]=[CH:5]2.[CH:18]1([C:21]([N:23]2[CH2:28][CH2:27][N:26]([C:29]3[CH:37]=[CH:36][C:32]([C:33]([O-])=[O:34])=[CH:31][CH:30]=3)[CH2:25][CH2:24]2)=[O:22])[CH2:20][CH2:19]1>>[CH:18]1([C:21]([NH:17][C:14]2[CH:15]=[CH:16][C:11]([N:7]3[C:8]4[C:4](=[CH:3][C:2]([NH:1][C:33](=[O:34])[C:32]5[CH:36]=[CH:37][C:29]([N:26]6[CH2:27][CH2:28][N:23]([C:21]([CH:18]7[CH2:19][CH2:20]7)=[O:22])[CH2:24][CH2:25]6)=[CH:30][CH:31]=5)=[CH:10][CH:9]=4)[CH:5]=[N:6]3)=[CH:12][CH:13]=2)=[O:22])[CH2:20][CH2:19]1参加物
3
実験手順
Compound 488 was prepared according to the procedure described in Scheme IV from 5-amino-1-(4-aminophenyl)indazole and 4-(4-cyclopropanecarbonylpiperazino)benzoate. [M+H]+ calcd for C32H32N6O3: 549.25; found: 549.16.
出典と根拠
- ORDレコード
- ord-b8d19a9632a8454bad514949545eb707
- 出典データセット
- uspto-grants-2015_09