1-Methoxy-3,4-dinitrobenzene → N-(1H-Indol-5-yl)-4-(6-methoxy-1H-benzo[d]imidazol-2-yl)benzamide

反応式

[N+:1]([C:4]1[CH:5]=[C:6]([O:13][CH3:14])[CH:7]=[CH:8][C:9]=1[N+:10]([O-])=O)([O-])=O.[NH:15]1[C:23]2[C:18](=[CH:19][C:20]([NH:24][C:25]([C:27]3[CH:34]=[CH:33][C:30]([CH:31]=O)=[CH:29][CH:28]=3)=[O:26])=[CH:21][CH:22]=2)[CH:17]=[CH:16]1>>[NH:15]1[C:23]2[C:18](=[CH:19][C:20]([NH:24][C:25](=[O:26])[C:27]3[CH:34]=[CH:33][C:30]([C:31]4[NH:1][C:4]5[CH:5]=[C:6]([O:13][CH3:14])[CH:7]=[CH:8][C:9]=5[N:10]=4)=[CH:29][CH:28]=3)=[CH:21][CH:22]=2)[CH:17]=[CH:16]1

参加物

反応物 2

HCID 128605041-Methoxy-3,4-dinitrobenzene

HCID 866740164-(5-Indolylaminocarbonyl)benzaldehyde

生成物 1

HCID 69674946N-(1H-Indol-5-yl)-4-(6-methoxy-1H-benzo[d]imidazol-2-yl)benzamide

実験手順

Compound 654 was prepared according to the procedure similar to that described in Scheme III from 3,4-dinitroanisole and 4-(5-indolylaminocarbonyl)benzaldehyde. [M+H]+ calcd for C23H18N4O2: 383.14; found: 383.01.

出典と根拠

ORDレコード: ord-4cd1eab6b0cb441ead4c7fa557e3c5e1
出典データセット: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09144557B2

反応ノート

読み込み中…