4-(4-Hydroxy-1-piperidinyl)benzoic acid → N-Cyclopropyl-4-(4-(4-(4-hydroxypiperidin-1-yl)benzamido)benzoyl)benzamide
反応式
[CH:1]1([NH:4][C:5](=[O:21])[C:6]2[CH:11]=[CH:10][C:9]([C:12](=[O:20])[C:13]3[CH:18]=[CH:17][C:16]([NH2:19])=[CH:15][CH:14]=3)=[CH:8][CH:7]=2)[CH2:3][CH2:2]1.[OH:22][CH:23]1[CH2:28][CH2:27][N:26]([C:29]2[CH:37]=[CH:36][C:32]([C:33](O)=[O:34])=[CH:31][CH:30]=2)[CH2:25][CH2:24]1>>[CH:1]1([NH:4][C:5](=[O:21])[C:6]2[CH:7]=[CH:8][C:9]([C:12](=[O:20])[C:13]3[CH:18]=[CH:17][C:16]([NH:19][C:33](=[O:34])[C:32]4[CH:31]=[CH:30][C:29]([N:26]5[CH2:27][CH2:28][CH:23]([OH:22])[CH2:24][CH2:25]5)=[CH:37][CH:36]=4)=[CH:15][CH:14]=3)=[CH:10][CH:11]=2)[CH2:3][CH2:2]1参加物
3
実験手順
Compound 687 was prepared according to the procedure described in Scheme IV from N-cyclopropyl-4-(4-aminobenzoyl)benzamide and 4-(4-hydroxypiperidin-1-yl)benzoic acid. [M+H]+ calcd for C29H30N3O4: 484.22; found: 484.08.
出典と根拠
- ORDレコード
- ord-b060d0b7bdd64e8fa9cf1a401d14f8a3
- 出典データセット
- uspto-grants-2015_09