Cyclopropylamine → HCID 67113045、化合物
反応式
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:19]=[CH:18][C:14]([C:15]([OH:17])=O)=[CH:13][CH:12]=1)[CH:6]=[CH:5]2.[CH:20]1([NH2:23])[CH2:22][CH2:21]1.[OH:24][CH2:25][CH2:26][N:27]1[C:35]2[C:30](=[CH:31][C:32]([C:36](O)=[O:37])=[CH:33][CH:34]=2)[CH:29]=[CH:28]1>>[CH:20]1([NH:23][C:15]([C:14]2[CH:18]=[CH:19][C:11]([N:7]3[C:8]4[C:4](=[CH:3][C:2]([NH:1][C:36]([C:32]5[CH:31]=[C:30]6[C:35](=[CH:34][CH:33]=5)[N:27]([CH2:26][CH2:25][OH:24])[CH:28]=[CH:29]6)=[O:37])=[CH:10][CH:9]=4)[CH:5]=[CH:6]3)=[CH:12][CH:13]=2)=[O:17])[CH2:22][CH2:21]1参加物
4
実験手順
Compound 947 was prepared according to the procedure described in Scheme IV from 4-(5-amino-1H-indol-1-yl)benzoic acid, cyclopropaneamine, and 1-(2-hydroxy ethyl)-1H-indole-5-carboxylic acid. [M+H]+ calcd for C29H26N4O3: 479.20; found: 479.01.
出典と根拠
- ORDレコード
- ord-9ca229f70f6d4555b4685f6b268e27fc
- 出典データセット
- uspto-grants-2015_09