Cyclopropylamine → HCID 67113041、化合物
反応式
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:19]=[CH:18][C:14]([C:15](O)=[O:16])=[CH:13][CH:12]=1)[CH:6]=[CH:5]2.[CH:20]1([NH2:23])[CH2:22][CH2:21]1.[CH3:24][N:25]1[CH2:30][CH2:29][N:28]([C:31]2[CH:39]=[CH:38][C:34]([C:35](O)=[O:36])=[CH:33][CH:32]=2)[CH2:27][CH2:26]1>>[CH:20]1([NH:23][C:15](=[O:16])[C:14]2[CH:18]=[CH:19][C:11]([N:7]3[C:8]4[C:4](=[CH:3][C:2]([NH:1][C:35](=[O:36])[C:34]5[CH:33]=[CH:32][C:31]([N:28]6[CH2:27][CH2:26][N:25]([CH3:24])[CH2:30][CH2:29]6)=[CH:39][CH:38]=5)=[CH:10][CH:9]=4)[CH:5]=[CH:6]3)=[CH:12][CH:13]=2)[CH2:22][CH2:21]1参加物
4
実験手順
Compound 961 was prepared according to the procedure described in Scheme IV from 4-(5-amino-1H-indol-1-yl)benzoic acid, cyclopropaneamine, and 4-(4-methylpiperazin-1-yl)benzoic acid. [M+H]+ calcd for C30H31N5O2: 494.25; found 494.06.
出典と根拠
- ORDレコード
- ord-bb3684b077634363a9975ebb5d217712
- 出典データセット
- uspto-grants-2015_09