Hydrochloric Acid → HCID 20543627、化合物

HRID 2286030ノート

反応式

HRID 2286030 の反応式
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10]([NH:12][C:13](=[O:19])[NH:14]C(C)(C)C)=[S:11].Cl>>[CH3:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([CH3:1])[C:3]=1[NH:9][C:10]([NH:12][C:13](=[O:19])[NH2:14])=[S:11]

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 20543608HCID 20543608、化合物

生成物 1

HCID 20543627HCID 20543627、化合物

実験手順

A mixture of 25.6 g. (0.1 mole) of 1-(2,6-dimethylphenyl)-3-(t-butylcarbamyl)thiourea and 200 ml. of conc. hydrochloric acid is refluxed for 1/2 hour. The reaction mixture is cooled, the solid filtered and washed with 10 ml. of 1:1 HCl/H2O and dried. The product is then recrystallized from ethanol-ether to obtain 1-(2,6-dimethylphenyl)-3-carbamylthiourea.

後処理

  1. additionA mixture of 25.6 g
  2. temperatureThe reaction mixture is cooled
  3. filtrationthe solid filtered
  4. washwashed with 10 ml
  5. dry with materialof 1:1 HCl/H2O and dried
  6. customThe product is then recrystallized from ethanol-ether

出典と根拠

ORDレコード
ord-543a09d208144b6fa7af7b655de6df9f
出典データセット
uspto-grants-1982_04
特許番号
US04326074

反応ノート

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