Acetic Acid → HCID 20542421、化合物

HRID 2286263ノート

反応式

HRID 2286263 の反応式
[CH3:1][O:2]/[N:3]=[C:4](/[C:7]1[CH:12]=[N:11][CH:10]=[CH:9][N:8]=1)\[C:5]#[N:6].C(O)(=[O:15])C.OO>O>[CH3:1][O:2]/[N:3]=[C:4](/[C:7]1[CH:12]=[N+:11]([O-:15])[CH:10]=[CH:9][N:8]=1)\[C:5]#[N:6]

参加物

5

反応物 3

HCID 176Acetic AcidHCID 784Hydrogen PeroxideHCID 957691779378-26-0

生成物 1

HCID 20542421HCID 20542421、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
70 °C

実験手順

A mixture of Z-α-methoxyiminopyrazineacetonitrile (4 g), acetic acid (15 ml) and 30% hydrogen peroxide in water (15 ml) was heated at a temperature of 70° C. over one night. The reaction mixture was concentrated and treated with water and chloroform. The chloroform layer was separated and dried over magnesium sulphate. Evaporation of the solvent and successive crystallization of the residue from alcohol afforded Z-α-methoxyimino-2-pyrazineacetonitrile-4-oxide, m.p. 144°-145° C.

後処理

  1. concentrationThe reaction mixture was concentrated
  2. additiontreated with water and chloroform
  3. customThe chloroform layer was separated
  4. dry with materialdried over magnesium sulphate
  5. customEvaporation of the solvent and successive crystallization of the residue from alcohol

出典と根拠

ORDレコード
ord-8935e49312484987aa8f2135c8c3ed0f
出典データセット
uspto-grants-1982_04
特許番号
US04327213

反応ノート

読み込み中…